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Cardinal RN, Aitken MRF (2006) ANOVA for the behavioural sciences researcher. Lawrence Erlbaum Associates, Inc., London Singer, B. F., Fadanelli, M., Kawa, A. B., & Robinson, T. E. (2018). Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? Journal of Neuroscience, 38(1), 60–73. doi:10.1523/JNEUROSCI.2458–17.2017. Deroche-Gamonet, V., Belin, D., & Piazza, P. V. (2004). Evidence for addiction-like behavior in the rat. Science, 305(5686), 1014–1017. doi:10.1126/science.1099020. Subjects were provided with water ad libitum throughout, and food (standard chow) was provided ad libitum until the start of training. After acclimation and habituation, rats were placed on a restricted diet of 15 g of chow per day (BioServ F-137 dustless pellets), which continued throughout behavioral training and experiments. Rats were weighed daily to ensure they maintained a minimum of 90% of pre-restriction body weight. Apparatus Paxinos G, Watson C (2007) The rat brain in stereotaxic coordinates. New York, NY: Academic Press. [ Google Scholar]

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Author Contributions

Desire and pleasure areas of the brain are activated by food, drugs, sex, and other pleasurable stimuli, as well as by cues linked to these stimuli. An important scientific discovery is that wanting (desire) and liking (pleasure) appear to be distinct experiences with different neural pathways. Wanting is the motivation to seek out and consume, and liking is the warm and fuzzy feeling of satisfaction. The urgent, intense, cravings of extreme wanting characteristic of addictive and compulsive behaviors may hold no pleasure whatsoever, and may even be distressing. Anderson, R.I., Bush, P.C., and Spear, L.P. (2013) Environmental manipulations alter age differences in attribution of incentive salience to reward-paired cues. Behavioural Brain Research 257, 83-89 The emergence of ST response is high if the reward follows the cue only some of the time, but only when training begins with partial reinforcement. When training begins with continuous reinforcement and then later adjusts to a partial reinforcement schedule, the incidence ST is low and does not increase.

Ko, C. H., Liu, G. C., Hsiao, S., Yen, J. Y., Yang, M. J., Lin, W. C., . . . Chen, C. S. (2009). Brain activities associated with gaming urge of online gaming addiction. Journal of Psychiatric Research, 43(7), 739–747. doi:10.1016/j.jpsychires.2008.09.012. Singer BF, Guptaroy B, Austin CJ, Wohl I, Lovic V, Seiler JL, Vaughan RA, Gnegy ME, Robinson TE, Aragona BJ (2016) Individual variation in incentive salience attribution and accumbens dopamine transporter expression and function. Eur J Neurosci 43:662–670. 10.1111/ejn.13134 Gilbertson, M. W., Shenton, M. E., Ciszewski, A., Kasai, K., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2002). Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nature Neuroscience, 5(11), 1242–1247. doi:10.1038/nn958.Fast, reliable parcel delivery across the UK. 1st Class Parcels aims to deliver parcels weighing up to 20kg the next working day, including Saturdays. It’s a fast, cost-effective UK-wide delivery service for customers that send less than 1,000 parcels per year. Schultz W, Dayan P, Montague PR (1997) A neural substrate of prediction and reward. Science 275:1593–1599. [ PubMed] [ Google Scholar] describes conditional responses that develop as a result of Pavlovian conditioning. Pavlovian conditional approach responses are characterized by cue-elicited approach behavior directed towards either the CS itself or the location of the US. Stimulus-substitution

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Litt, A., Khan, U., and Shiv, B. (2010) Lusting while loathing: Parallel counterdriving of wanting and liking. Psychological Science 21(1), 118-125.Frank, G. K., Shott, M. E., Riederer, J., & Pryor, T. L. (2016). Altered structural and effective connectivity in anorexia and bulimia nervosa in circuits that regulate energy and reward homeostasis. Translational Psychiatry, 6(11), e932. doi:10.1038/tp.2016.199. Cancellation your Service may cause the loss of Content, features, or capacity of your Account. The Company does not accept any liability for such loss. 13. Indemnity. Myin-Germeys, I., Delespaul, P. A., & deVries, M. W. (2000). Schizophrenia patients are more emotionally active than is assumed based on their behavior. Schizophrenia Bulletin, 26(4), 847–854.

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